Glucagon delivery - An overview of current and future devices.

Arthur Rabinovich, Ronny Priefer

Diabetes & metabolic syndrome 2021 Jul-Aug

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Glucagon is crucial in the treatment of Type 1 diabetes mellitus due to the prevalence of hypoglycemia in patients with this disorder. Hypoglycemia can be life-threatening, leading to loss of consciousness, and requiring emergency glucagon to reverse the effects. Emergency kits are difficult to use, requiring reconstitution of glucagon, which itself is not stable for lengthy periods. Approaches have aimed to improve stability which has allowed for use in pens or pumps. Glucagon can now also be delivered intranasally. This review discusses the history of glucagon, its current delivery methods as well as some modern approaches being introduced. Copyright © 2021 Diabetes India. Published by Elsevier Ltd. All rights reserved.

Citation

Arthur Rabinovich, Ronny Priefer. Glucagon delivery - An overview of current and future devices. Diabetes & metabolic syndrome. 2021 Jul-Aug;15(4):102155