Deep Eutectic Solvents (DESs) and Their Application in Biosensor Development.

Deep Eutectic Solvents (DESs) are a new class of solvents characterized by a remarkable decrease in melting point compared to those of the starting components. The eutectic mixtures can be simply prepared by mixing a Hydrogen Bond Acceptor (HBA) with a Hydrogen Bond Donor (HBD) at a temperature of about 80 °C. They have found applications in different research fields; for instance, they have been employed in organic synthesis, electrochemistry, and bio-catalysis, showing improved biodegradability and lower toxicity compared to other solvents. Herein, we review the use of DESs in biosensor development. We consider the emerging interest in different fields of this green class of solvents and the possibility of their use for the improvement of biosensor performance. We point out some promising examples of approaches for the assembly of biosensors exploiting their compelling characteristics. Furthermore, the extensive ability of DESs to solubilize a wide range of molecules provides the possibility to set up new devices, even for analytes that are usually insoluble and difficult to quantify.

Citation

Rossella Svigelj, Nicolò Dossi, Cristian Grazioli, Rosanna Toniolo. Deep Eutectic Solvents (DESs) and Their Application in Biosensor Development. Sensors (Basel, Switzerland). 2021 Jun 22;21(13)

Mesh Tags

Substances

PMID: 34206344

search → result