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The role of topical non-steroidal anti-inflammatory drugs (NSAIDs) in routine cataract surgery has been established since decades. Topical NSAIDs have been shown to reduce postoperative ocular inflammation and pain, preserve intraoperative mydriasis, and reduce the risk of postoperative cystoid macular oedema, whilst carrying a very low side-effect profile. Nepafenac is one of the currently available topical NSAIDs. The studies have shown that is has a high ocular penetration, allowing for potentially better results than other NSAIDs. This review gathers the current literature on the role of nepafenac in cataract surgery aiming to help surgeons maximise the benefits of its use to achieve improved surgical outcomes.


Athanasios Bezatis, Ioanna Georgou, John Dedes, Panagiotis Theodossiadis, Irini Chatziralli. Nepafenac in cataract surgery. Clinical & experimental optometry. 2022 Apr;105(3):263-267

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PMID: 34210237

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