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Teaching an old dog new tricks: repurposing β-lactams.
Trends in pharmacological sciences 2021 AugSizes of these terms reflect their relevance to your search.
Recently, Martelli and colleagues reported on the structural and functional characterization of new antimycobacterials based on N-thio-β-lactams. Surprisingly, the inhibitory mechanism follows a path unexpected for β-lactams, providing an alternative route to defeat drug-resistant strains of Mycobacterium tuberculosis. Copyright © 2021 Elsevier Ltd. All rights reserved.
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Vega Miguel-Ruano, Juan A Hermoso. Teaching an old dog new tricks: repurposing β-lactams. Trends in pharmacological sciences. 2021 Aug;42(8):617-619
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PMID: 34215443
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