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To evaluate the influence of insufficient bone cement distribution on outcomes following percutaneous vertebroplasty (PVP). This retrospective matched-cohort study included patients 50-90 years of age who had undergone PVP for single level vertebral compression fractures (VCFs) from February 2015 to December 2018. Insufficient (Group A)/sufficient (Group B) distribution of bone cement in the fracture area was assessed from pre- and post-operative computed tomography (CT) images. Assessments were before, 3-days post-procedure, and at the last follow-up visit (≥12 months). Of the 270 eligible patients, there were 54 matched pairs. On post-operative day 3 and at the last follow-up visit, significantly greater visual analogue scale (VAS) pain scores and Oswestry Disability Index (ODI) scores were obtained in Group B over Group A, while kyphotic angles (KAs) and vertebral height (VH) loss were significantly larger in Group A compared with Group B. Incidence of asymptomatic cement leakage and re-collapse of cemented vertebrae were also greater in Group A compared with Group B. Insufficient cement distribution may relate to less pain relief and result in progressive vertebral collapse and kyphotic deformity post-PVP.


Ling Mo, Zixian Wu, De Liang, Linqiang Y, Zhuoyan Cai, Jinjing Huang, Shunxin Lin, Jianchao Cui, Shuncong Zhang, Zhidong Yang, Zhensong Yao, Xiaobing Jiang. Influence of bone cement distribution on outcomes following percutaneous vertebroplasty: a retrospective matched-cohort study. The Journal of international medical research. 2021 Jul;49(7):3000605211022287

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PMID: 34233516

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