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Protein-protein interaction networks have a crucial role in biological processes. Proteins perform multiple functions in forming physical and functional interactions in cellular systems. Information concerning an enormous number of protein interactions in a wide range of species has accumulated and has been integrated into various resources for molecular biology and systems biology. This chapter provides a review of the representative databases and the major computational methods used for protein-protein interactions.


Natsu Nakajima, Tatsuya Akutsu, Ryuichiro Nakato. Databases for Protein-Protein Interactions. Methods in molecular biology (Clifton, N.J.). 2021;2361:229-248

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PMID: 34236665

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