Effectiveness of a multidisciplinary care program for the management of venous thromboembolism in cancer patients: a pilot study.

Journal of thrombosis and thrombolysis 2022 Feb

filter terms:

Treatment of Venous thromboembolism (VTE) in cancer patients is challenging due to higher risk of VTE recurrence or bleeding under anticoagulants. We assessed the effectiveness of a dedicated "Allo-Thrombosis Cancer" multidisciplinary care program (AlloTC-MCP) that incorporated individualized care, regular follow-ups, telephone counselling, and a patient education program. From September 2017 to October 2019, 100 consecutive cancer patients with new VTE onset were enrolled in this observational single-center prospective pilot study and received standard (control group, n = first 50 patients enrolled) or AlloTC-MCP care (n = next 50 patients enrolled) over a 6-month VTE treatment follow-up period. Primary end-point was the percentage of adherence to the International Clinical Practice Guidelines (ITAC-CPGs) at 6 (M6) month follow-up. Among the 100 patients with different cancer types (22% genitourinary, 19% breast, 16% gastrointestinal, 15% lymphoma, 11% lung and 17% others), 51 patients (61%) had metastatic disease and 31 (31%) received chemotherapy alone. Main baseline cancer and VTE clinical characteristics did not differ between the 2 groups. Adherence rates to ITAC-CPGs was significantly higher in the AlloTC-MCP group (100% (M0), 72% (M3) and 68% (M6)) compared with the control group (84% (M0), 8% (M3) and 16% (M6)). Quality of Life (QoL) was significantly improved in the AlloTC-MCP group 6 months after inclusion. The "AlloTC-MCP" was associated with improved adherence to ITAC-CPGs and merits further expansion. © 2021. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

Citation

Ilham Benzidia, Benjamin Crichi, Claire Montlahuc, Hanadi Rafii, Arlette N'Dour, Maxime Sebuhyan, Hélène Gauthier, Nassim Ait Abdallah, Philippe Benillouche, Stéphane Villiers, Christine Le Maignan, Dominique Farge. Effectiveness of a multidisciplinary care program for the management of venous thromboembolism in cancer patients: a pilot study. Journal of thrombosis and thrombolysis. 2022 Feb;53(2):417-424