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Opioid dependence syndrome (ODS) is a chronic relapsing remitting condition associated with significant impairment and mortality risk. Opioid substitution therapy is used worldwide, but long-term retention rates are low and there is risk of misuse and diversion. Yoga practice can improve quality of life, reduce chronic pain, and enhance endogenous opioids (beta-endorphins). We describe a case of ODS where yoga was added to the conventional management and who was followed up for 9 months. Assessments were done for clinical symptoms, urine drug screening, plasma beta-endorphins, and Buprenorphine dosage. We observed an improvement in his clinical symptoms and reduction in the requirements for Buprenorphine. A slight increase in basal plasma beta-endorphin levels was also observed at the 9-month follow-up (from 2.02 pmol/L at baseline to 6.51 pmol/L). Copyright © 2021 Prateek Varshney et al.


Prateek Varshney, Hemant Bhargav, Pilli Devi Vidyasagar, Sumana Venugopal, Rashmi Arsappa, Venkata Lakshmi Narasimha, Priyamvada Sharma, Vijayashree Rao, Pratima Murthy. Yoga as an Adjunct for Management of Opioid Dependence Syndrome: A Nine-Month Follow-Up Case Report. Case reports in psychiatry. 2021;2021:5541995

PMID: 34336342

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