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This study reports a case of a 49-year-old woman having B-cell acute lymphoblastic leukemia with glycophorin A, a representative erythroid marker, expression. According to the WHO criteria for mixed phenotype acute leukemia (MPAL), erythroid lineage is not defined, and to the best of our knowledge, only one other case with erythroid/B-cell biphenotypic acute leukemia has been reported previously. To establish the disease entity and clarify the pathophysiology of erythroid/lymphoid MPAL, additional cases need to be analyzed.


Yosuke Matsumoto, Mio Sugitani, Rina Nishikawa, Hiroaki Nagata, Nobuki Iwamoto, Kodai Kuriyama, Muneo Ohshiro, Yoshiko Hirakawa, Toshiki Iwai, Tohru Inaba, Hitoji Uchiyama. B-cell acute lymphoblastic leukemia with glycophorin A expression]. [Rinsho ketsueki] The Japanese journal of clinical hematology. 2021;62(7):717-720

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PMID: 34349053

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