Triterpenoids from the bark of Entandrophragma angolense.

Binh T D Trinh, Dzung N Bui, Ly T T Nguyen, Hieu T Nguyen, Chi N Nguyen, Lien-Hoa D Nguyen, Tuyen N M Huynh, Tien T C Cao, Le-Thu T Nguyen

Natural product research 2023 Jan

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Two new triterpenoids, entanolide (1) and methyl 3,4-secotirucalla-23-oxo-4(28),7,24-trien-21-al-3-oate (2), together with nine known compounds (3-11), were isolated from the bark of Entandrophragma angolense. Their structures were elucidated based on spectroscopic analyses, mainly 1 D and 2 D NMR spectral data. Compounds 1-6 and 8 were evaluated for their cytotoxicity against HepG2 cells, and compounds 2-5 exhibited weak activities.

Citation

Binh T D Trinh, Dzung N Bui, Ly T T Nguyen, Hieu T Nguyen, Chi N Nguyen, Lien-Hoa D Nguyen, Tuyen N M Huynh, Tien T C Cao, Le-Thu T Nguyen. Triterpenoids from the bark of Entandrophragma angolense. Natural product research. 2023 Jan;37(2):240-247