Carbamazepine-induced immune thrombocytopenia confirmed by modified MASPAT test.

A 76-year-old man suffering post-herpetic neuralgia developed severe thrombocytopenia 15 days after the administration of carbamazepine. Carbamazepine-dependent platelet antibodies were proved to be present in the patient's serum by a modified Monoclonal Antibody Solid-phase Platelet Antibody Test (MASPAT), and the diagnosis of carbamazepine-induced immune thrombocytopenia was confirmed. For the patient, carbamazepine should be advised to be avoided permanently. The present report advocated the application of a modified MASPAT test for the detection of carbamazepine-dependent platelet antibodies. Copyright © 2021 Elsevier Ltd. All rights reserved.

Citation

Weiyuan Chen, Xiaoying Lv, Ruiming Rong, Boting Wu. Carbamazepine-induced immune thrombocytopenia confirmed by modified MASPAT test. Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis. 2021 Dec;60(6):103228

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PMID: 34364794

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