NMR reveals the interplay between SilE and SilB model peptides in the context of silver resistance.

SilE and SilB are both proteins involved in the silver efflux pump found in Gram-negative bacteria such as S. typhimurium. Using model peptides along with NMR and CD experiments, we show how SilE may store silver ions prior to delivery and we hypothesize for the first time the interplay between SilB and SilE.

Citation

Lucille Babel, Minh-Ha Nguyen, Cédric Mittelheisser, Marie Martin, Katharina M Fromm, Olivier Walker, Maggy Hologne. NMR reveals the interplay between SilE and SilB model peptides in the context of silver resistance. Chemical communications (Cambridge, England). 2021 Sep 11;57(70):8726-8729

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PMID: 34396382

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