Matthaios Didagelos, Areti Pagiantza, Thomas Zegkos, Christos Papanastasiou, Konstantina Zarra, Vasileios Angelopoulos, Antonios Kouparanis, Emmanouela Peteinidou, George Sianos, Haralambos Karvounis, Antonios Ziakas
Future cardiology 2022 FebRadial artery occlusion (RAO) is the commonest complication of transradial catheterization. There is no evidence-based therapy, in the frame of a randomized control study, for the treatment of RAO. The purpose of the LOW-RAO study is to question the hypothesis if low-molecular-weight heparin is effective in the treatment of RAO after transradial coronary catheterization (both angiography and percutaneous coronary intervention). It is a prospective, open label, randomized controlled trial that will randomize 60 patients with RAO, irrespective of symptoms, into two groups, one receiving anticoagulation with low-molecular-weight heparin and the other receiving no treatment. The primary end point is improvement in radial artery patency rate at 4 weeks after the procedure. Clinical trial registration number: NCT04196309 (ClinicalTrials.gov).
Matthaios Didagelos, Areti Pagiantza, Thomas Zegkos, Christos Papanastasiou, Konstantina Zarra, Vasileios Angelopoulos, Antonios Kouparanis, Emmanouela Peteinidou, George Sianos, Haralambos Karvounis, Antonios Ziakas. Low-molecular-weight heparin in radial artery occlusion treatment: the LOW-RAO randomized study. Future cardiology. 2022 Feb;18(2):91-100
PMID: 34397270
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