Correlation Engine 2.0
Clear Search sequence regions

  • dna marker (1)
  • female (1)
  • genotypes (1)
  • Goat (7)
  • litter size (4)
  • nucleotides (2)
  • pregnancy (1)
  • PRNT (4)
  • SNPs (1)
  • Sizes of these terms reflect their relevance to your search.

    Our previous study has firstly pointed that three nucleotide variants (g.-11C > T, g.117A > G, and g.149C > T) of the goat PRNT gene can significantly influence litter size. Given litter size is positively correlated with growth performance, we consider whether the PRNT gene also acts on the growth performance in goats. In this work, a correlation analysis among different litter size types and growth traits of Shaanbei white cashmere (SBWC) goats was performed, and results showed that a positive correlation did exist in our detected population (P < 0.01). Then, the association among different genotypes of three variations and goat growth performance was measured. Our results pointed to g.117A > G being significantly associated with the cannon circumference (P = 4.60E-05) while no significant effect was found between another two SNPs and growth traits after the Bonferroni's correction (P*n < 0.05). Together, this is the first report about the influence of the PRNT gene on the growth of goat and g.117A > G can be regarded as a possible DNA marker applying for MAS breeding.


    Yi Bi, Bihao Luo, Shaoli Zhang, Jie Li, Yuta Yang, Xianyong Lan, Chuanying Pan. Investigation of Genetic Effects of Nucleotide Variants Within the Goat PRNT Gene on Growth Performance. Animal biotechnology. 2023 Apr;34(2):321-326

    Expand section icon Mesh Tags

    Expand section icon Substances

    PMID: 34424814

    View Full Text