Antiviral Activity of Carrageenans and Processing Implications.

Milena Álvarez-Viñas, Sandra Souto, Noelia Flórez-Fernández, Maria Dolores Torres, Isabel Bandín, Herminia Domínguez

Marine drugs 2021 Jul 30

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Carrageenan and carrageenan oligosaccharides are red seaweed sulfated carbohydrates with well-known antiviral properties, mainly through the blocking of the viral attachment stage. They also exhibit other interesting biological properties and can be used to prepare different drug delivery systems for controlled administration. The most active forms are λ-, ι-, and κ-carrageenans, the degree and sulfation position being determined in their properties. They can be obtained from sustainable worldwide available resources and the influence of manufacturing on composition, structure, and antiviral properties should be considered. This review presents a survey of the antiviral properties of carrageenan in relation to the processing conditions, particularly those assisted by intensification technologies during the extraction stage, and discusses the possibility of further chemical modifications.

Citation

Milena Álvarez-Viñas, Sandra Souto, Noelia Flórez-Fernández, Maria Dolores Torres, Isabel Bandín, Herminia Domínguez. Antiviral Activity of Carrageenans and Processing Implications. Marine drugs. 2021 Jul 30;19(8)