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RAB6 GTPase is the most abundant Golgi-associated RAB protein and regulates several transport steps at the level of this organelle. Homozygous Rab6a knockout (k/o) is embryonic lethal in mouse. To study RAB6 function in cell lineages and tissues, we thus generated various conditional Rab6a knockout (k/o) mice using the Cre/lox system. © 2021. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.


Sabine Bardin, Bruno Goud. Generating Rab6 Conditional Knockout Mice. Methods in molecular biology (Clifton, N.J.). 2021;2293:257-263

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PMID: 34453723

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