Role of repressed microRNAs in endometriosis.

Kaei Nasu, Yoko Aoyagi, Ruofei Zhu, Mamiko Okamoto, Mitsutake Yano, Kentaro Kai, Yasushi Kawano

Medical molecular morphology 2022 Mar

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Endometriosis is a common, estrogen-dependent benign tumor that affect 3-10% women of reproductive age, and is characterized by the ectopic growth of endometrial tissue, which is found primarily in the rectovaginal septum, ovaries, and pelvic peritoneum. To date, accumulating evidence suggests that various epigenetic aberrations, including the expression of aberrant microRNAs (miRNAs), play definite roles in the pathogenesis of endometriosis. This review summarizes the recent findings on the aberrantly repressed miRNAs, as well as their potential roles regarding the pathogenesis of endometriosis. © 2021. The Japanese Society for Clinical Molecular Morphology.

Citation

Kaei Nasu, Yoko Aoyagi, Ruofei Zhu, Mamiko Okamoto, Mitsutake Yano, Kentaro Kai, Yasushi Kawano. Role of repressed microRNAs in endometriosis. Medical molecular morphology. 2022 Mar;55(1):1-7