Hard bilateral syphilitic testes with vasculitis: a case report and literature review.

We report the case of a patient with syphilitic testicular gumma and vasculitis with adrenal failure due to chronic steroid use. A 63-year-old male presented with hard right eye swelling and very firm bilateral testes on palpation, which he had for 2 years. Testicular tumor markers were negative; syphilis test was positive. Radiological examination suggested aortitis and bilateral testicular malignancy. The patient received ampicillin for the infection and prednisolone for vasculitis. Left orchidectomy was performed to confirm the presence of testicular tumor; histological examinations revealed granulomatous orchitis. The prednisolone doses were adjusted because of relapses and adverse effects of steroid use. Unfortunately, the patient died in the intensive care unit because of uncontrolled blood pressure and pneumonia. This is a rare case of syphilis with testicular involvement and vasculitis. This report shows the importance of broadening the differential diagnoses of testicular firmness. © 2021. The Author(s).

Citation

Sat Prasad Nepal, Takehiko Nakasato, Takashi Fukagai, Takeshi Shichijo, Jun Morita, Yoshiko Maeda, Kazuhiko Oshinomi, Yoshihiro Nakagami, Tsutomu Unoki, Tetsuo Noguchi, Tatsuki Inoue, Ryosuke Kato, Satoshi Amano, Moyuru Mizunuma, Masahiro Kurokawa, Yoshiki Tsunokawa, Sou Yasuda, Yoshio Ogawa. Hard bilateral syphilitic testes with vasculitis: a case report and literature review. BMC urology. 2021 Sep 03;21(1):120

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PMID: 34479520

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