Battle of the Crystalloids in the Operating Room: A Literature Review.

The purpose of this article is to synthesize the evidence regarding the commonalities and differences between the three most common crystalloid solutions used in the operating room (normal saline [NS], lactated Ringer's [LR], and Plasmalyte [PL]) in order to determine best practice. This study is an integrative review of literature. A review of the literature was conducted using the PubMed, CINAHL Plus, and Cochrane Library databases. The inclusion criteria included adult patients undergoing surgery who received either NS, LR, and/or PL (or similar solutions) for fluid maintenance therapy. A total of 15 articles from 2008 to 2020 conducted in a surgical setting were selected for the review; eleven randomized controlled studies, three observational studies, and one cohort-controlled trial. The findings suggest balanced crystalloid solutions are superior to NS in the operating room in terms of maintaining a stable acid-base balance. PL is preferable to LR because it most closely resembles plasma concentration. Future research is needed to determine the cost-effectiveness of the solutions. Copyright © 2021 American Society of PeriAnesthesia Nurses. Published by Elsevier Inc. All rights reserved.

Citation

Alejandra Salinero, Greta Mitzova-Vladinov. Battle of the Crystalloids in the Operating Room: A Literature Review. Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses. 2021 Dec;36(6):629-637

Mesh Tags

Substances

PMID: 34479770

search → result