Using the World Apheresis Association Registry Helps to Improve the Treatment Quality of Therapeutic Apheresis.

Bernd Stegmayr, Elizabeth Newman, Volker Witt, Kurt Derfler, Gerda Leitner, Sunny Eloot, Annemieke Dhondt, Dries Deeren, Jan Ptak, Milan Blaha, Mirka Lanska, Zdenka Gasova, Zdenka Bhuiyan-Ludvikova, Radomira Hrdlickova, Wolfgang Ramlow, Heinrich Prophet, Jan T Kielstein, Giancarlo Liumbruno, Elena Mori, Antanas Griskevicius, Judita Audzijoniene, Hans Vrielink, Eva Rombout-Sestrienkova, Astrid Aandahl, Aleksandar Sikole, Jorge Tomaz, Katarina Lalic, Ines Bojanic, Virginia Strineholm, Bo Brink, Gösta Berlin, Josefina Dykes, Thomas Nilsson, Torsten Eich, Henrik Hadimeri, Gunilla Welander, Sandra Ortega Sanchez, Osman Ilhan, Colwyn Poole

Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie 2021 Aug

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Therapeutic apheresis (TA) is prescribed to patients that suffer from a severe progressive disease that is not sufficiently treated by conventional medications. A way to gain more knowledge about this treatment is usually by the local analysis of data. However, the use of large quality assessment registries enables analyses of even rare findings. Here, we report some of the recent data from the World Apheresis Association (WAA) registry. Data from >104,000 procedures were documented, and TA was performed on >15,000 patients. The main indication for TA was the collection of autologous stem cells (45% of patients) as part of therapy for therapy. Collection of stem cells from donors for allogeneic transplantation was performed in 11% of patients. Patients with indications such as neurological diseases underwent plasma exchange (28%). Extracorporeal photochemotherapy, lipid apheresis, and antibody removal were other indications. Side effects recorded in the registry have decreased significantly over the years, with approximately only 10/10,000 procedures being interrupted for medical reasons. Collection of data from TA procedures within a multinational and multicenter concept facilitates the improvement of treatment by enabling the analysis of and feedback on indications, procedures, effects, and side effects. Copyright © 2021 by S. Karger AG, Basel.

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PMID: 34539317

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