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In pandemic situations like COVID 19, real time monitoring of patient condition and continuous delivery of inspired oxygen can be made possible only through artificial intelligence-based system modeling. Even now manual control of mechanical ventilator parameters is continuing despite the ever-increasing number of patients in critical epidemic conditions. Here a suggestive multi-layer perceptron neural network model is developed to predict the level of inspired oxygen delivered by the mechanical ventilator along with mode and positive end expiratory pressure (PEEP) changes for reducing the effort of health care professionals. The artificial neural network model is developed by Python programming using real time data. Parameter identification for model inputs and outputs is done by in corporating consistent real time patient data including periodical arterial blood gas analysis, continuous pulse oximetry readings and mechanical ventilator settings using statistical pairwise analysis using R programming. Mean square error values and R values of the model are calculated and found to be an average of 0.093 and 0.81 respectively for various data sets. Accuracy loss will be in good fit with validation loss for a comparable number of epochs. Comparison of the model output is undertaken with physician's prediction using statistical analysis and shows an accuracy error of 4.11 percentages which is permissible for a good predictive system. © 2021 Elsevier Ltd. All rights reserved.


Sita Radhakrishnan, Suresh G Nair, Johney Isaac. Multilayer perceptron neural network model development for mechanical ventilator parameters prediction by real time system learning. Biomedical signal processing and control. 2022 Jan;71:103170

PMID: 34567236

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