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Modulation of membrane-cytoskeleton interactions: ezrin as key player.

Lei-Miao Yin, Michael Schnoor

Trends in cell biology 2022 Feb


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    Membrane-cytoskeleton interactions (MCIs) are mediated by actin-binding proteins (ABPs). Ezrin is a crucial ABP that links membranes to actin filaments during lamellipodia formation, cell polarization, and migration. We discuss the concept of MCI and the potential of ezrin as a druggable target for treating inflammatory diseases and cancers. Copyright © 2021 Elsevier Ltd. All rights reserved.

    Citation

    Lei-Miao Yin, Michael Schnoor. Modulation of membrane-cytoskeleton interactions: ezrin as key player. Trends in cell biology. 2022 Feb;32(2):94-97

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    PMID: 34625363

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