Enzymatic Alteration of ECM to Explore Muscle Function and Motor Control of a Learned Behavior.

Caitlin Mencio, Kuberan Balagurunathan, Franz Goller

Methods in molecular biology (Clifton, N.J.) 2022

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Nerves and muscle interact to perform learned motor behavior such as birdsong. Glycosaminoglycans play a major role in the function of muscle as well as the formation and function of the neuromuscular junction. The alteration of GAG chains provides a unique opportunity to alter muscle behavior and thus motor control of a behavior. This chapter provides a method for observing the effects on mature birdsong of removal of GAG chains within syringeal muscle. © 2022. Springer Science+Business Media, LLC, part of Springer Nature.

Citation

Caitlin Mencio, Kuberan Balagurunathan, Franz Goller. Enzymatic Alteration of ECM to Explore Muscle Function and Motor Control of a Learned Behavior. Methods in molecular biology (Clifton, N.J.). 2022;2303:487-493