Correlation Engine 2.0
Clear Search sequence regions

Sizes of these terms reflect their relevance to your search.

Erythromycin fermentation dregs (EFD) as one kind of organic-rich biosolid was of great potential for methane production. However, the influence of residual erythromycin (ERY) on the anaerobic digestion process of EFD remains unclear. In this study, a batch test was conducted with different ERY concentrations to investigate its effects on methanogenesis. The antibiotic resistance genes and microbial community composition were analyzed to explore the potential mechanism. The results showed that more than 80% of ERY was removed after 30 days digestion. Furthermore, 100, 200 and 300 mg/L of ERY presented no significant effect on the performance of anaerobic digestion. Instead, a high concentration of ERY (500 mg/L) increased 13% rather than inhibited the methane yields. Moreover, the proliferation of the methylase gene (e.g., ermA/T) was promoted under the high pressure of ERY. The relative abundance of acetogenic bacteria (Sedimentibacter) and mixotrophic archaea (Methanosarcina) were enhanced, indicating that their syntrophic association would play the dominant role in the stimulating effects of methanogenesis. Copyright © 2021 Elsevier B.V. All rights reserved.


Mengmeng Wang, Peng Ren, Yafei Wang, Chen Cai, Huiling Liu, Xiaohu Dai. Erythromycin stimulates rather than inhibits methane production in anaerobic digestion of antibiotic fermentation dregs. The Science of the total environment. 2022 Feb 10;807(Pt 3):151007

Expand section icon Mesh Tags

Expand section icon Substances

PMID: 34666088

View Full Text