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Diet Therapeutics Interventions for Obesity: A Systematic Review and Network Meta-Analysis.

Mina Morsali, Jalal Poorolajal, Fatemeh Shahbazi, Aliasghar Vahidinia, Amin Doosti-Irani

Journal of research in health sciences 2021 Sep 19


filter terms:
  • behavior (1)
  • camellia (1)
  • catechin (1)
  • data analysis (1)
  • diet (5)
  • diet therapeutics (3)
  • high- fat diet (1)
  • high- protein diet (1)
  • humans (1)
  • inulin (2)
  • low (3)
  • low fat diet (1)
  • meta analysis (5)
  • patients overweight (2)
  • weight loss (4)
    • Sizes of these terms reflect their relevance to your search.

    Up to now, different diet therapeutics interventions have been introduced for the treatment of obesity. The present study aimed to compare the diet therapeutics interventions for obesity simultaneously. Systematic review and network meta-analysis METHODS: The major international databases, including Medline (via PubMed), Web of Science, Scopus, Cochrane Library, and Embase, were searched using a predesigned search strategy. Randomized controlled trials (RCTs) that had compared the diet therapy interventions were included. The mean difference with a 95% confidence interval was used to summarize the effect size in the network meta-analysis. The frequentist approach was used for data analysis. In total, 36 RCTs out of 9335 retrieved references met the inclusion criteria in this review. The included RCTs formed nine independent networks. Based on the results, Hypocaloricdiet+Monoselect Camellia (MonCam, P=0.99), energy restriction, behavior modification+exercise (LED) (P=0.99), sweetener at 20% of total calories (HFCS20)+Ex (P=0.67), catechin-richgreentea(650)+inulin (P=0.68), very low calorie diet (VLCD) (P=1.00), normal protein diet+resistance exercise (NPD+RT) (P=0.80), low-calorie diets+exercise (Hyc+Ex) (P=0.85), high-soy-protein low-fat diet (SD) (P=0.75), calorie restriction+behavioral weight loss (Hyc+BWL) (P=0.99) were the better treatments for weight loss in the networks one to nine, respectively. Based on the results of network meta-analysis, it seems that Hypocaloricdiet+MonCam, LED, HFCS20+Ex, catechin-rich green tea +inulin, VLCD, NPD+RT, Hyc+Ex, SD, Hyc+BWL, are the better treatments for weight loss in patients with overweight and obesity.

    Citation

    Mina Morsali, Jalal Poorolajal, Fatemeh Shahbazi, Aliasghar Vahidinia, Amin Doosti-Irani. Diet Therapeutics Interventions for Obesity: A Systematic Review and Network Meta-Analysis. Journal of research in health sciences. 2021 Sep 19;21(3):e00521

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    PMID: 34698655

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