In this elegant study, Evrard et al. (2021. J. Exp. Med.https://doi.org/10.1084/jem.20210116) find that sphingosine 1-phosphate receptor 5 (S1PR5) powerfully impairs tissue-resident memory T cell (TRM) formation, and that tissue-derived TGF-β limits S1pr5 expression by infiltrating T cells. © 2021 Hallisey and Schwab.
Citation
Victoria M Hallisey, Susan R Schwab. Blood-thirsty: S1PR5 and TRM. The Journal of experimental medicine. 2022 Jan 03;219(1)
Mesh Tags
Substances
PMID: 34714328
View Full Text
