Cyclic pyrimidines cCMP and cUMP were known to be present in a variety of organisms and cell types, but their biological roles remained mysterious. Tal et al. show that bacteria use cCMP and cUMP as second messengers that function in anti-phage defense. Crown Copyright © 2021. Published by Elsevier Inc. All rights reserved.
Karen L Maxwell. Cyclic pyrimidines jump on the anti-phage bandwagon. Cell. 2021 Nov 11;184(23):5691-5693
PMID: 34767773
View Full Text