A new diphenylheptanoid from the rhizomes of Curcuma zedoaria.

Truong Nhat Van Do, Hai Xuan Nguyen, Tho Huu Le, Phu Hoang Dang, Mai Thanh Nguyen, Mai Thanh Thi Nguyen, Nhan Trung Nguyen

Zeitschrift fur Naturforschung. C, Journal of biosciences 2022 May 25

filter terms:

A phytochemical investigation of the rhizomes of Curcuma zedoaria was carried out, leading to the isolation of a new diphenylheptanoid, zedoaroxane A (1), together with four known compounds (2-5). Their structures were elucidated based on NMR spectroscopic data. All isolated compounds possessed α-glucosidase inhibitory activity, with the IC50 values ranging from 35.2 to 89.0 µM, more potent than that of the positive control acarbose (IC50, 214.5 µM). © 2021 Walter de Gruyter GmbH, Berlin/Boston.

Citation

Truong Nhat Van Do, Hai Xuan Nguyen, Tho Huu Le, Phu Hoang Dang, Mai Thanh Nguyen, Mai Thanh Thi Nguyen, Nhan Trung Nguyen. A new diphenylheptanoid from the rhizomes of Curcuma zedoaria. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2022 May 25;77(5-6):219-223