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A phytochemical investigation of the rhizomes of Curcuma zedoaria was carried out, leading to the isolation of a new diphenylheptanoid, zedoaroxane A (1), together with four known compounds (2-5). Their structures were elucidated based on NMR spectroscopic data. All isolated compounds possessed α-glucosidase inhibitory activity, with the IC50 values ranging from 35.2 to 89.0 µM, more potent than that of the positive control acarbose (IC50, 214.5 µM). © 2021 Walter de Gruyter GmbH, Berlin/Boston.


Truong Nhat Van Do, Hai Xuan Nguyen, Tho Huu Le, Phu Hoang Dang, Mai Thanh Nguyen, Mai Thanh Thi Nguyen, Nhan Trung Nguyen. A new diphenylheptanoid from the rhizomes of Curcuma zedoaria. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2022 May 25;77(5-6):219-223

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PMID: 34787385

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