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In this work, we used photodynamic therapy(ALA-PDT) to treat 2 patients with perianal hemorrhoids combined with condyloma acuminatum. After 4 photodynamic treatments, the condyloma acuminata skin lesions completely disappeared. At the same time, we unexpectedly found that the patient's hemorrhoids skin lesions had mostly faded, and did not reappear during the half-year follow-up. Photodynamic therapy is satisfactory in the treatment of hemorrhoids combined with condyloma acuminatum, and the recurrence rate is low. We also have found that photodynamic therapy is equally effective on hemorrhoid skin lesions. PDT may be adopted as a new strategy in the study and treatment of hemorrhoids. To the best of our knowledge, no such cases have been reported. Copyright © 2021. Published by Elsevier B.V.


Lin Liu, Guo Wei, Qingqing Xu, Chunmin Zhang, Chunhong Zhang, Liya Meng, Ying Liu. Photodynamic therapy in the treatment of perianal condyloma acuminatum with hemorrhoids: A report of two cases. Photodiagnosis and photodynamic therapy. 2022 Mar;37:102644

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PMID: 34823031

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