Digestion and absorption properties of Lycium barbarum polysaccharides stabilized selenium nanoparticles.

Jixian Zhang, Xue Yang, Tao Ji, Chaoting Wen, Zhiqiang Ye, Xiaofang Liu, Li Liang, Guoyan Liu, Xin Xu

Food chemistry 2022 Mar 30

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In the present study, the digestion and absorption properties of Lycium barbarum polysaccharides stabilized selenium nanoparticles (LBP-SeNPs) were investigated. The results showed that selenium nanoparticles (SeNPs) exhibited a higher selenium release rate than LBP-SeNPs (p＜0.05) after being digested in the stages of oral cavity, stomach and intestine. During the digestion process, the particle size of the LBP-SeNPs and SeNPs were both significantly increased, but the particle size of LBP-SeNPs was significantly smaller than that of SeNPs. The results of TEM further indicated that LBP-SeNPs can better maintain the morphology and properties of nanoparticles. Besides, the experiments of the intestinal sac model showed that LBP-SeNPs can better promote the absorption of selenium in various parts (duodenum, jejunum and ileum) of the intestine. Therefore, the LBP can help to improve the structural stability of SeNPs in the digestion process and improve the bioavailability of selenium. Copyright © 2021 Elsevier Ltd. All rights reserved.

Citation

Jixian Zhang, Xue Yang, Tao Ji, Chaoting Wen, Zhiqiang Ye, Xiaofang Liu, Li Liang, Guoyan Liu, Xin Xu. Digestion and absorption properties of Lycium barbarum polysaccharides stabilized selenium nanoparticles. Food chemistry. 2022 Mar 30;373(Pt B):131637