The light-absorbing retina has an exceptionally high oxygen demand, which imposes two conflicting needs: high rates of blood perfusion and an unobstructed light path devoid of blood vessels. This review discusses mechanisms and physiological trade-offs underlying retinal oxygen supply in vertebrates and examines how these physiological systems supported the evolution of vision.
Christian Damsgaard, Michael W Country. The Opto-Respiratory Compromise: Balancing Oxygen Supply and Light Transmittance in the Retina. Physiology (Bethesda, Md.). 2022 Mar 01;37(2):101-113
PMID: 34843655
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