Cytokine storm in tuberculosis and IL-6 involvement.

Funmilayo Grâce Boni, Insaf Hamdi, Liadrine Moukendza Koundi, Kanchan Shrestha, Jianping Xie

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 2022 Jan

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Tuberculosis is probably the most seasoned illness of the humanity. Intricacies or subsequent death emerging from these infections are frequently connected with cytokine storm. Interleukin-6 (IL-6) plays a crucial role in the immune response to tuberculosis. Therefore, there is a need to research some new therapeutic approaches to block IL-6 signaling that are right now being applied to the M. tuberculosis. In this review, we investigate the implication of IL-6 in the context of tuberculosis research. Copyright © 2021. Published by Elsevier B.V.

Citation

Funmilayo Grâce Boni, Insaf Hamdi, Liadrine Moukendza Koundi, Kanchan Shrestha, Jianping Xie. Cytokine storm in tuberculosis and IL-6 involvement. Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 2022 Jan;97:105166