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Cancer stem cells (CSCs) are known for their superior tumor-initiating and tumor-repopulating potential, partly reflecting their pronounced ability to evade immune recognition. Liu and colleagues recently identified a new aldehyde dehydrogenase (ALDH)-dependent mechanism whereby triple-negative breast CSCs evade immunosurveillance upon recruitment of myeloid-derived suppressor cells. Copyright © 2021 Elsevier Ltd. All rights reserved.
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Carlos Jiménez-Cortegana, Claudia Galassi, Lorenzo Galluzzi. MDSCs sneak CSCs out of (immuno)surveillance. Trends in immunology. 2022 Jan;43(1):1-3
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PMID: 34863632
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