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Salicylic acid (SA) is a plant hormone almost exclusively associated with the promotion of immunity. It is also known that SA has a negative impact on plant growth, yet only limited efforts have been dedicated to explain this facet of SA action. In this review, we focus on SA-related reduced growth and discuss whether it is a regulated process and if the role of SA in immunity imperatively comes with growth suppression. We highlight molecular targets of SA that interfere with growth and describe scenarios where SA can improve plant immunity without a growth penalty. Copyright © 2021 Elsevier Ltd. All rights reserved.


Igor Pokotylo, Michael Hodges, Volodymyr Kravets, Eric Ruelland. A ménage à trois: salicylic acid, growth inhibition, and immunity. Trends in plant science. 2022 May;27(5):460-471

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PMID: 34872837

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