The role of IL-8 in the chronic airway inflammation and its research progress].

Xian Li, Jingyun Li, Yuan Zhang, Luo Zhang

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 2021 Dec

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Chronic rhinosinusitis（CRS）, asthma and chronic obstructive pulmonary disease（COPD） are common chronic airway inflammatory diseases, which seriously affect patients' quality of life and bring heavy economic and social burden. Interleukin（IL） -8 is an important chemokine of neutrophils and other inflammatory cells, which plays an important role in the development of chronic airway inflammation. In this review, the inflammatory mechanisms involved in regulating IL-8 gene expression and the role of IL-8 in different airway chronic inflammation were reviewed. Copyright© by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.

Citation

Xian Li, Jingyun Li, Yuan Zhang, Luo Zhang. The role of IL-8 in the chronic airway inflammation and its research progress]. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery. 2021 Dec;35(12):1144-1148