High-Sensitivity Troponin T For The Risk Assessment Of Patients With Acute Atrial Fibrillation.

Elevations of high-sensitivity troponin T (Hs-TnT) in the setting of acute atrial fibrillation (AF) are not clearly understood. This study evaluated factors associated with these elevations and its prognostic implication. We prospectively included 413 consecutive patients who presented to our institution with acute AF. The median Hs-TnT on admission was 12 ng/l and 39.4% had values above the 99th percentile. At 1-year, AF recurrence occurred in 38.3% of patients, and MACE in 5.6%. Hs-TnT levels were not associated with AF reversion (p 0.869) or with 1-year AF recurrence (p 0.132) but they were with MACE (12 vs 24 ng/l, p 0.001). Thus, Hs-TnT was a strong predictor of MACE (HR 3.486, 95% CI 1.256-5.379, p 0.009) in this population. In conclusion, Hs-TnT elevation was frequently observed in patients with acute AF, and although it was not associated with AF reversion or recurrence, it was highly predictive of MACE at 1-year. Copyright © 2021 Elsevier Inc. All rights reserved.

Citation

Marcia Cortés, Rosina Arbucci, Florencia Lambardi, Juan Furmento, Florencia Muñoz, Marcos Viruel, Bryce Alexander, Adrian Baranchuk, Juan Pablo Costabel. High-Sensitivity Troponin T For The Risk Assessment Of Patients With Acute Atrial Fibrillation. Current problems in cardiology. 2022 Nov;47(11):101079

Mesh Tags

Substances

PMID: 34923030

search → result