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Extensive Dermatophytosis Caused by Terbinafine-Resistant Trichophyton indotineae, France.

Arnaud Jabet, Sophie Brun, Anne-Cecile Normand, Sebastien Imbert, Mohammad Akhoundi, Eric Dannaoui, Laeticia Audiffred, Francois Chasset, Arezki Izri, Liliane Laroche, Renaud Piarroux, Claude Bachmeyer, Christophe Hennequin, Alicia Moreno Sabater

Emerging infectious diseases 2022 Jan


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    Extensive dermatophytosis caused by terbinafine-resistant Trichophyton indotineae harboring Phe397Leu and Leu393Ser substitutions in the squalene epoxidase enzyme was diagnosed in France. Analysis of internal transcribed spacer sequences revealed the wide spread of this species in Asia and Europe. Detection of T. indotineae in animals suggests their possible role as reservoirs.

    Citation

    Arnaud Jabet, Sophie Brun, Anne-Cecile Normand, Sebastien Imbert, Mohammad Akhoundi, Eric Dannaoui, Laeticia Audiffred, Francois Chasset, Arezki Izri, Liliane Laroche, Renaud Piarroux, Claude Bachmeyer, Christophe Hennequin, Alicia Moreno Sabater. Extensive Dermatophytosis Caused by Terbinafine-Resistant Trichophyton indotineae, France. Emerging infectious diseases. 2022 Jan;28(1):229-233

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    PMID: 34932456

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