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Geminiviruses reprogram host machineries to ensure their own propagation. They do not encode any DNA polymerase. Furthermore, the absence of direct evidence about the precise role of any host-encoded DNA polymerase has made geminivirus replication an enigma. Wu et al. recently resolved this puzzle by revealing that geminiviruses utilize plant DNA polymerase α and δ to drive their replication. Copyright © 2021 Elsevier Ltd. All rights reserved.


Dibyendu Ghosh, Supriya Chakraborty. Selective REcruitmeNt of plant DNA polymerases by geminivirus. Trends in genetics : TIG. 2022 Mar;38(3):211-213

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PMID: 34949465

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