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    The aim of the study is to evaluate the effectiveness of a number of popular fluorine-containing caries prophylactic drugs by determining the level of solubility of tooth enamel in laboratory conditions. For testing fluorine-containing preparations, three observation groups were formed: Group I - using the preparation with the content of fluorides 4%; Group II - with a preparation for deep fluoridation of enamel, consisting of a liquid saturated with fluorine, copper and magnesium, as well as a suspension of calcium hydroxide; Group III - with a three-component gel based on carboxymethyl cellulose (CMC) the content of fluorides 1.5%. The study was carried out by using the method of «enamel windows» and modeling in the laboratory the processes of both natural and pathological solubility of tooth enamel and determining the level of its solubility by analyzing the decalcifying solution of the oral fluid for the content of calcium and phosphorus ions in it. In the course of the study of fluorinated karyoprophylactic preparations on the enamel surface, according to the observation group, the most active karyoprophylactic fluorinated compositions were identified. The data obtained from laboratory studies allow us to formulate clear recommendations for practical health care for the most effective use of the properties of the tested fluorine-containing drugs for prophylactic purposes or in relation to the therapy of focal demineralization of enamel: to obtain the most effective result of the prevention of dental caries in the conditions of practical dental treatment, we recommend applying gel fluoride preparations, and in the treatment of initial caries of the enamel of the teeth, give preference to systems for deep fluoridation of the enamel of the teeth.


    O V Matskieva, G I Skripkina, A P Solonenko, V I Samokhina, A E Matsygorova. Influence of fluoride preparations for the prevention of dental caries on the enamel solubility]. Stomatologiia. 2021;100(6):13-16

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    PMID: 34953182

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