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Stereoselective Palladium-Catalyzed Arylation of Exo-Glycals with Aryl Iodides.

Jeffery Regier, Supriya Ghanty, Yuri Bolshan

The Journal of organic chemistry 2022 Jan 07


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    A novel methodology for the arylation of exo-glycals has been developed. A range of exo-glycals underwent reactions with aryl iodides in the presence of a palladium catalyst. The transformation proceeded in a stereoselective manner to afford Z-isomers. The developed transformation demonstrated excellent functional group tolerance.

    Citation

    Jeffery Regier, Supriya Ghanty, Yuri Bolshan. Stereoselective Palladium-Catalyzed Arylation of Exo-Glycals with Aryl Iodides. The Journal of organic chemistry. 2022 Jan 07;87(1):524-530

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    PMID: 34958570

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