Studying Autophagy In Vivo in the Mammary Gland and in Xenograft Samples.

Zhongju Zou, Álvaro F Fernández, Verena Jendrossek, Silvia Vega-Rubín-de-Celis

Methods in molecular biology (Clifton, N.J.) 2022

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Autophagy is a dynamic process that can be monitored in multiple ways, both in vitro and in vivo. Studies in mice are a widely used tool to understand multiple diseases and conditions where autophagy plays a role, and therefore autophagic flux measurement in tissues of rodent models are of utmost importance. Here, we present some assays successfully used in determining the autophagy status in the mice mammary gland as well as in xenografts. © 2022. The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature.

Citation

Zhongju Zou, Álvaro F Fernández, Verena Jendrossek, Silvia Vega-Rubín-de-Celis. Studying Autophagy In Vivo in the Mammary Gland and in Xenograft Samples. Methods in molecular biology (Clifton, N.J.). 2022;2445:255-272