Olmesartan-associated Enteropathy].

Long Zou, Qiang Wang, Yue Li, Ai-Ming Yang

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 2021 Dec 30

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Olmesartan,an angiotensin Ⅱ receptor blocker,is a commonly used antihypertensive drug.Several case reports and cohort studies in recent years have described a severe gastrointestinal adverse event with chronic diarrhea,intestinal malabsorption,and weight loss after the administration of olmesartan.In such cases,the patients recovered after discontinuing olmesartan.This adverse effect is called olmesartan-associated enteropathy(OAE).This article reviews the potential pathogenesis and clinical characteristics of OAE,which broadens the disease spectrum for the differential diagnosis of chronic diarrhea and intestinal malabsorption.

Citation

Long Zou, Qiang Wang, Yue Li, Ai-Ming Yang. Olmesartan-associated Enteropathy]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. 2021 Dec 30;43(6):986-990