Juan Wang, Shuai Liu, Yangen Huang, Xiu-Hua Xu, Feng-Ling Qing
Chemical communications (Cambridge, England) 2022 Jan 27The first C-H trifluoroethylamination of heteroarenes with previously unknown N-trifluoroethyl hydroxylamine reagents was achieved under photoredox catalyzed conditions. In the presence of an iridium(III) photoredox catalyst, a variety of heteroarenes, such as indoles, benzofurans, and benzothiophenes, were smoothly converted to the trifluoroethylaminated products in moderate to high yields and with excellent regioselectivity.
Juan Wang, Shuai Liu, Yangen Huang, Xiu-Hua Xu, Feng-Ling Qing. Photoredox catalyzed C-H trifluoroethylamination of heteroarenes. Chemical communications (Cambridge, England). 2022 Jan 27;58(9):1346-1349
PMID: 34986214
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