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Crohn's disease (CD) is a chronic inflammatory disease of the gastrointestinal tract. Achieving clinical and endoscopic remission is the main therapeutic goal.1 Despite available treatment options, some patients present with treatment-refractory disease to approved therapies.2 Randomized clinical trials enable a standardized evaluation of drugs with new modes of action. However, eligibility criteria are strict excluding those with ostomy or failures to other medication leaving a considerable proportion of patients noneligible.3. Copyright © 2023 AGA Institute. Published by Elsevier Inc. All rights reserved.

Citation

Jagoda Pokryszka, Sieglinde Reinisch, Christian Primas, Gottfried Novacek, Walter Reinisch. Induction Efficacy of Upadacitinib in Therapy-Refractory Crohn's Disease: A Retrospective Case Series. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2023 Feb;21(2):532-534.e3

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PMID: 35033640

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