Correlation Engine 2.0
Clear Search sequence regions


  • cell wall (1)
  • FtsZ (5)
  • tubulin (1)
  • Sizes of these terms reflect their relevance to your search.

    Less than a handful of cuboid and squared cells have been described in nature, which makes them a rarity. Here, we show how Candidatus Thiosymbion cuboideus, a cube-like gammaproteobacterium, reproduces on the surface of marine free-living nematodes. Immunostaining of symbiont cells with an anti-fimbriae antibody revealed that they are host-polarized, as these appendages exclusively localized at the host-proximal (animal-attached) pole. Moreover, by applying a fluorescently labeled metabolic probe to track new cell wall insertion in vivo, we observed that the host-attached pole started septation before the distal one. Similarly, Ca. T. cuboideus cells immunostained with an anti-FtsZ antibody revealed a proximal-to-distal localization pattern of this tubulin homolog. Although FtsZ has been shown to arrange into squares in synthetically remodeled cuboid cells, here we show that FtsZ may also mediate the division of naturally occurring ones. This implies that, even in natural settings, membrane roundness is not required for FtsZ function. © 2021 The Author(s).

    Citation

    Philipp M Weber, Gabriela F Paredes, Tobias Viehboeck, Nika Pende, Jean-Marie Volland, Olivier Gros, Michael VanNieuwenhze, Jörg Ott, Silvia Bulgheresi. FtsZ-mediated fission of a cuboid bacterial symbiont. iScience. 2022 Jan 21;25(1):103552


    PMID: 35059602

    View Full Text