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Determining the structural plasticity and dynamics of nuclear pore complexes (NPCs) are major challenges. In this issue of Cell, Akey et al. present comprehensive NPC structures from in vitro and in vivo preparations, demonstrating multiple NPC forms in single cells while providing insight into the evolutionary origin of NPC architecture. Copyright © 2021 Elsevier Inc. All rights reserved.


Megan R McCarthy, C Patrick Lusk. One ring doesn't rule them all: Distinct nuclear pore complexes in a single cell. Cell. 2022 Jan 20;185(2):230-231

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PMID: 35063070

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