Biocompatibility of NbTaTiVZr with Surface Modifications for Osteoblasts.

We report a potential biomedical material, NbTaTiVZr, and the impact of surface roughness on the osteoblast culture and later behavior based on in vitro tests of preosteoblasts. Cell activities such as adhesion, viability, and typical protein activity on NbTaTiVZr showed comparable results with that of commercially pure Ti (CP-Ti). In addition, NbTaTiVZr with a smooth surface exhibits better cell adhesion, viability, and typical protein activity which shows that surface modification can improve the biocompatibility of NbTaTiVZr. This supports the biological evidence and shows that NbTaTiVZr can potentially be evaluated as a biomedical material for clinical use.

Citation

Shih-Jie Lin, Jia-An Lin, Wei Yu, Chanho Lee, Chun-Yu Hung, Jonathan D Poplawsky, Peter K Liaw, Yi-Chia Chou. Biocompatibility of NbTaTiVZr with Surface Modifications for Osteoblasts. ACS applied bio materials. 2022 Feb 21;5(2):642-649

Mesh Tags

Substances

PMID: 35080840

search → result