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Poststroke depression (PSD) is a syndrome that occurs after stroke. The efficacy of Chinese herbal medicine (CHM) for PSD has also received widespread attention, but there is still a lack of clinical evidence because this overview evaluates the published meta-analyses (MAs)/Systematic reviews (SRs). To provide evidence for the clinical application of CHM in the treatment of PSD. Two researchers searched 7 databases for SRs/MAs which are about randomized controlled trials on CHM for PSD. Two investigators use the systematic review assessment tool (AMSTAR-2), the risk of bias in systematic scale, the list of preferred reporting items for systematic reviews and meta-analysis, and the classification of recommended assessments for evaluation, development and evaluation system to assess the included SRs/MAs. Our findings will be published in peer-reviewed journals. This study provides evidence-based medical evidence for the impact of CHM on PSD. INPLASY202210001. Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc.


Hongshuo Shi, Cengda Dong, Wenbin Liu, Min Peng, Guomin Si, Fengshan Sun. Quality of evidence supporting the role of Chinese herbal medicine for the treatment of poststroke depression: A protocol for systematic review and meta-analysis. Medicine. 2022 Jan 28;101(4):e28707

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PMID: 35089232

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