MRSA surveillance programmes worldwide: moving towards a harmonised international approach.

Multinational surveillance programmes for methicillin-resistant Staphylococcus aureus (MRSA) are dependent on national structures for data collection. This study aimed to capture the diversity of national MRSA surveillance programmes and to propose a framework for harmonisation of MRSA surveillance. The International Society of Antimicrobial Chemotherapy (ISAC) MRSA Working Group conducted a structured survey on MRSA surveillance programmes and organised a webinar to discuss the programmes' strengths and challenges as well as guidelines for harmonisation. Completed surveys represented 24 MRSA surveillance programmes in 16 countries. Several countries reported separate epidemiological and microbiological surveillance. Informing clinicians and national policy-makers were the most common purposes of surveillance. Surveillance of bloodstream infections (BSIs) was present in all programmes. Other invasive infections were often included. Three countries reported active surveillance of MRSA carriage. Methodology and reporting of antimicrobial susceptibility, virulence factors, molecular genotyping and epidemiological metadata varied greatly. Current MRSA surveillance programmes rely upon heterogeneous data collection systems, which hampers international epidemiological monitoring and research. To harmonise MRSA surveillance, we suggest improving the integration of microbiological and epidemiological data, implementation of central biobanks for MRSA isolate collection, and inclusion of a representative sample of skin and soft-tissue infection cases in addition to all BSI cases. Copyright © 2022. Published by Elsevier Ltd.

Citation

Valérie O Baede, Michael Z David, Arjana Tambic Andrasevic, Dominique S Blanc, Michael Borg, Grainne Brennan, Boudewijn Catry, Aurélie Chabaud, Joanna Empel, Hege Enger, Marie Hallin, Marina Ivanova, Andreas Kronenberg, Kuntaman Kuntaman, Anders Rhod Larsen, Katrien Latour, Jodi A Lindsay, Bruno Pichon, Dewi Santosaningsih, Leo M Schouls, François Vandenesch, Guido Werner, Dorota Żabicka, Helena Žemličková, Harald Seifert, Margreet C Vos, MRSA Surveillance Worldwide Study Group (ISAC), the ESCMID Study Group for Nosocomial Infections (ESGNI), the ESCMID Study Group for Staphylococci and Staphylococcal Diseases (ESGS). MRSA surveillance programmes worldwide: moving towards a harmonised international approach. International journal of antimicrobial agents. 2022 Mar;59(3):106538

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PMID: 35091055

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