Surgical Treatment for Pneumothorax and Tumor-bronchial Fistula Secondary to Pulmonary Metastasis of Osteosarcoma in Pediatric and Adolescent Patients.

Pneumothorax and tumor-bronchial fistula are rare complications of pulmonary metastasis of osteosarcoma. We herein report the cases of 3 pediatric and adolescent patients who developed pneumothorax or tumor-bronchial fistula during treatment of pulmonary metastasis of osteosarcoma with chemotherapeutics or antiangiogenic agents. Two patients developed pneumothorax, and the other patient developed tumor-bronchial fistula. All of the patients finally underwent the surgery to treat their complications. Although it is not a curative surgery, surgery for pneumothorax and tumor-bronchial fistula is acceptable. The operative procedure should be considered on the basis of the predicted prognosis of the patient. Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.

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Naonori Kawakubo, Tomoro Hishiki, Ayumu Arakawa, Miho Nakajima, Tadashi Kumamoto, Kazuo Nakagawa, Akira Kawai, Chitose Ogawa. Surgical Treatment for Pneumothorax and Tumor-bronchial Fistula Secondary to Pulmonary Metastasis of Osteosarcoma in Pediatric and Adolescent Patients. Journal of pediatric hematology/oncology. 2022 Oct 01;44(7):393-397

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PMID: 35091523

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